CD74 antibody (HLA-DR-gamma) (FITC)

Details for Product anti-CD74 Antibody No. ABIN2472424
Antigen
  • DHLAG
  • HLADG
  • II
  • Ia-GAMMA
  • CLIP
  • Ii
  • INVG34
  • Iclp-1
  • iclp1
  • wu:fb11f09
  • wu:fb12a01
  • wu:fb13d06
  • wu:fk94e07
  • CD74 molecule
  • CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
  • CD74 molecule, major histocompatibility complex, class II invariant chain a
  • CD74
  • Cd74
  • cd74a
Reactivity
Human
520
121
31
27
Host
Mouse
446
103
4
2
Clonality (Clone)
Monoclonal ()
Conjugate
This CD74 antibody is conjugated to FITC
33
32
25
20
19
16
14
9
9
9
9
9
9
9
9
9
8
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
342
330
234
134
98
95
63
61
58
54
16
13
10
2
2
2
2
2
1
1
Options
Immunogen B lymphoblastoid cell line HFB1.
Clone Bu45
Isotype IgG1
Characteristics Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC)
Plasmids, Primers & others Plasmids, Primers & others CD74 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name CD74 (CD74 Antibody Abstract)
Gene ID 972
UniProt P04233
Pathways Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.1 mg/mL
Product cited in: Lapaque, Jahnke, Trowsdale, Kelly: "The HLA-DRalpha chain is modified by polyubiquitination." in: The Journal of biological chemistry, Vol. 284, Issue 11, pp. 7007-16, 2009 (PubMed).

Beswick, Bland, Suarez, Barrera, Fan, Reyes: "Helicobacter pylori binds to CD74 on gastric epithelial cells and stimulates interleukin-8 production." in: Infection and immunity, Vol. 73, Issue 5, pp. 2736-43, 2005 (PubMed).

Background publications Wraight, van Endert, Möller, Lipp, Ling, MacLennan, Koch, Moldenhauer: "Human major histocompatibility complex class II invariant chain is expressed on the cell surface." in: The Journal of biological chemistry, Vol. 265, Issue 10, pp. 5787-92, 1990 (PubMed).

Chaves, Cruz, Gomes, Domingues, Marques da Silva, Veloso: "Hepatic amebiasis, analysis of 56 cases. I. Clinical findings." in: The American journal of gastroenterology, Vol. 68, Issue 2, pp. 134-9, 1977 (PubMed).

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