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Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 2 (KCNA2) antibody Primary Antibody

KCNA2 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN265022
$586.30
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0.1 mg
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  • Target
    Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 2 (KCNA2)
    Reactivity
    • 35
    • 20
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 35
    • 9
    Rabbit
    Clonality
    • 37
    • 8
    Polyclonal
    Conjugate
    • 24
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Un-conjugated
    Application
    • 38
    • 19
    • 18
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    This antibody reacts to Kv1.2 Potassium Channel.
    Purification
    Purified
    Immunogen
    Synthetic peptide derived from the rat Kv1.2 potassium channel conjugated to KLH.
    Isotype
    IgG
  • Application Notes
    Western Blot: 5 - 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate buffered saline with 0.08 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • Target
    Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 2 (KCNA2)
    Alternative Name
    KCNA2 (KCNA2 Antibody Abstract)
    Synonyms
    KCNA2, kcna2, HBK5, HK4, HUKIV, KV1.2, MK2, NGK1, RBK2, Akr6a4, ENSMUSG00000074335, Gm10672, Kca1-2, Kv1.2, Mk-2, BK2, XSha2, k(v)1.2, kcna2-a, kv1.2, potassium voltage-gated channel subfamily A member 2, potassium channel, voltage gated shaker related subfamily A, member 1, potassium voltage-gated channel, shaker-related subfamily, member 2, potassium channel, voltage gated shaker related subfamily A, member 2 S homeolog, KCNA2, kcna1, Kcna2, LOC100537815, kcna2.S
    Background
    The Kv1.2 potassium channel is a voltage-gated channel protein which belongs to the delayed rectifier class and to the Shaker potassium channel subfamily which includes Kv1.1, Kv1.3, Kv1.4 and Kv1.5. Potassium channels are mainly found in plasma membranes but are not generally distributed over the cell surface. Potassium channels catalyze the rapid permeation of potassium ions while rejecting biologically abundant potential competitors such as sodium, calcium and magnesium. Ion selectivity and high through put rate of potassium channels is accomplished by precise co-ordination of dehydrated potassium by the protein and multiple ion occupancy within the permeation pathway. All potassium channels carry out the formation of a transmembrane leak specific for potassium ions. Since cells almost universally maintain cytoplasmic potassium concentrations higher than those extracellularly, the opening of a potassium channel implies a negative ongoing change in electrical voltage across the cell membrane. This may result in termination of the action potential of electrically excitable cells including nerve, muscle and pancreatic beta cells. In non-excitable cells, potassium channels play important roles in the cellular potassium recycling required for electrolyte balance effected by the renal epithelium.Synonyms: HBK5, HUKIV, KCNA2, NGK1, Potassium voltage-gated channel subfamily A member 2, Voltage-gated potassium channel subunit Kv1.2
    Gene ID
    3737
    NCBI Accession
    NP_004965
    UniProt
    P16389
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