Cadherin 5 antibody (Alexa Fluor 647)

Catalog No. ABIN2657634

Product Details anti-Cadherin 5 Antibody (Alexa Fluor 647)

Target: Cadherin 5 (CDH5)

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Cadherin 5 antibody is conjugated to Alexa Fluor 647

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Neutralization (Neut), Intracellular Flow Cytometry (ICFC), Cytometry by Time of Flight (CyTOF)

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

Clone: VECD1

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for Cadherin 5

Target: Cadherin 5 (CDH5)

Alternative Name: CD144 (CDH5 Products)

Background: CD144, also known as vascular endothelial-cadherin (VE-cadherin), is a 120 kD member of the type II Cadherin family. It is an endothelial specific hemophilic adhesion molecule involved in endothelial cell survival, migration, contact-dependent growth inhibition and homophilic adhesion. VE-cadherin is essential for maintaining the integrity of the endothelial barrier in vivo.

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2