C-Type Lectin Domain Family 1, Member B (CLEC1B) antibody (PE)
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- Target See all C-Type Lectin Domain Family 1, Member B (CLEC1B) Antibodies
- C-Type Lectin Domain Family 1, Member B (CLEC1B)
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- PE
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Application
- Intracellular Flow Cytometry (ICFC)
- Purification
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
- Clone
- 17D9-CLEC2
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product CLEC1B Primary Antibody
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anti-C-Type Lectin Domain Family 1, Member B (CLEC1B) (AA 128-229) antibody
CLEC1B Reactivity: Human WB, ELISA, IP Host: Mouse Monoclonal 1C10 unconjugated
anti-C-Type Lectin Domain Family 1, Member B (CLEC1B) (AA 68-229), (Extracellular Domain) antibodyCLEC1B Reactivity: Human FACS, IP, ICC Host: Mouse Monoclonal AYP1 unconjugated
anti-C-Type Lectin Domain Family 1, Member B (CLEC1B) (AA 55-229) antibodyCLEC1B Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-C-Type Lectin Domain Family 1, Member B (CLEC1B) (AA 68-229), (Extracellular Domain) antibody (PE)CLEC1B Reactivity: Human FACS Host: Mouse Monoclonal AYP1 PE
anti-C-Type Lectin Domain Family 1, Member B (CLEC1B) (AA 68-229), (Extracellular Domain) antibody (APC)CLEC1B Reactivity: Human FACS Host: Mouse Monoclonal AYP1 APC
anti-C-Type Lectin Domain Family 1, Member B (CLEC1B) antibody (PE)CLEC1B Reactivity: Mouse FACS Host: Rat Monoclonal 17D9 PE
anti-C-Type Lectin Domain Family 1, Member B (CLEC1B) (AA 1-100) antibodyCLEC1B Reactivity: Human ELISA, FACS, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-C-Type Lectin Domain Family 1, Member B (CLEC1B) (AA 44-78) antibodyCLEC1B Reactivity: Human WB Host: Rabbit Polyclonal RB57434 unconjugated
anti-C-Type Lectin Domain Family 1, Member B (CLEC1B) (Internal Region) antibodyVerified CLEC1B Reactivity: Human WB, ELISA Host: Goat Polyclonal unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.2 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Protect from prolonged exposure to light. Do not freeze.
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- C-Type Lectin Domain Family 1, Member B (CLEC1B)
- Alternative Name
- CLEC2 (CLEC1B Products)
- Target Type
- Viral Protein
- Background
- CLEC-2, also known as CLEC1B and CLEC1B1, is C-type lectin-like receptor with a single cytoplasmic YXXL sequence known as a hem-immunoreceptor tyrosine-based activation motif (hemITAM). CLEC-2 is highly expressed on resting platelets and megakaryocytes and at a lower levels on several hematopoietic cells including monocytes, macrophages, dendritic cells, and granulocytes. The first ligand that was identified for CLEC-2 was the snake venom toxin rhodocytin, podoplanin has also been identified as an endogenous ligand for CLEC-2. Exposure of platelets to rhodocytin leads tyrosine phosphorylation of the ITAM-like motif and Syk-dependent platelet activation. CLEC-2 also functions as an activation receptor on monoyctes and neutrophils to induce phagocytosis and proinflammatory cytokine production.
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