C-Type Lectin Domain Family 1, Member B (CLEC1B) (AA 68-229), (Extracellular Domain) antibody

Catalog No. ABIN7505968

The Mouse Monoclonal anti-C-Type Lectin Domain Family 1, Member B antibody is suitable to detect C-Type Lectin Domain Family 1, Member B in samples from Human. It has been validated for FACS, IP and ICC.

Quick Overview for C-Type Lectin Domain Family 1, Member B (CLEC1B) (AA 68-229), (Extracellular Domain) antibody (ABIN7505968)

Target: C-Type Lectin Domain Family 1, Member B (CLEC1B)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: AYP1

Product Details

Binding Specificity: AA 68-229, Extracellular Domain

Purpose: Anti-Hu CLEC2 Purified

Characteristics: The mouse monoclonal antibody AYP1 recognizes an epitope within the extracellular part of CLEC2, a transmembrane glycoprotein expressed on activated plateles and on platelet microparticles.

Purification: Purified by protein-A affinity chromatography.

Immunogen: A recombinant extracellular domain of human CLEC2 (amino acids 68-229)

Isotype: IgG1, kappa

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details

Target: C-Type Lectin Domain Family 1, Member B (CLEC1B)

Alternative Name: CLEC2

Background: C-type lectin domain family 1 member B,CLEC2 (C-type lectin-like receptor 2) functions as a platelet receptor for the lymphatic endothelial marker, PDPN, and mediates platelet activation. Besides platelets, it can be found on myeloid cells and NK cells. CLEC2 functions also as an attachment factor for HIV-1 and facilitates its capture by platelets. Platelet-aggregating snake venom protein rhodocytin also binds to CLEC2.,CLEC1B, CLEC2B, PRO1384, QDED721

Gene ID: 51266

UniProt: Q9P126