C-Type Lectin Domain Family 1, Member B (CLEC1B) (AA 68-229), (Extracellular Domain) antibody (PE)

Catalog No. ABIN7505970

This Mouse Monoclonal antibody specifically detects C-Type Lectin Domain Family 1, Member B in FACS. It exhibits reactivity toward Human.

Quick Overview for C-Type Lectin Domain Family 1, Member B (CLEC1B) (AA 68-229), (Extracellular Domain) antibody (PE) (ABIN7505970)

Target: C-Type Lectin Domain Family 1, Member B (CLEC1B)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: PE

Application: Flow Cytometry (FACS)

Clone: AYP1

Product Details

Binding Specificity: AA 68-229, Extracellular Domain

Purpose: Anti-Hu CLEC2 PE

Characteristics: The mouse monoclonal antibody AYP1 recognizes an epitope within the extracellular part of CLEC2, a transmembrane glycoprotein expressed on activated plateles and on platelet microparticles.

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: A recombinant extracellular domain of human CLEC2 (amino acids 68-229)

Isotype: IgG1, kappa

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze,Protect from prolonged exposure to light

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details

Target: C-Type Lectin Domain Family 1, Member B (CLEC1B)

Alternative Name: CLEC2

Background: C-type lectin domain family 1 member B,CLEC2 (C-type lectin-like receptor 2) functions as a platelet receptor for the lymphatic endothelial marker, PDPN, and mediates platelet activation. Besides platelets, it can be found on myeloid cells and NK cells. CLEC2 functions also as an attachment factor for HIV-1 and facilitates its capture by platelets. Platelet-aggregating snake venom protein rhodocytin also binds to CLEC2.,CLEC1B, CLEC2B, PRO1384, QDED721

Gene ID: 51266

UniProt: Q9P126