TNFRSF11A antibody (PE)

Catalog No. ABIN2663246

Product Details anti-TNFRSF11A Antibody (PE)

Target: TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This TNFRSF11A antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: R12-31

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for TNFRSF11A

Target: TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))

Alternative Name: CD265 (TNFRSF11A Products)

Background: CD265 is a type I transmembrane protein also known as receptor activator of NF-κB (RANK), tumor necrosis factor receptor superfamily member 11A (TNFRSF11A), and osteoclast differentiation factor receptor (ODFR). RANK is a receptor for RANK ligand/TRANCE/OPGL and is involved in osteoclastogenesis and T cell/dendritic cell interactions. RANK is ubiquitously expressed in trabecular bone, thymus, small intestine, lung, brain, and kidney.

Pathways: NF-kappaB Signaling