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TNFRSF11A Products

(Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))

Categories

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012].

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Featured TNFRSF11A Categories

TNFRSF11A Antibodies

High quality antibodies with extensive validation data.

TNFRSF11A ELISA Kits

Reliable ELISA kits for a wide range of species.

TNFRSF11A Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TNFRSF11A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7434629
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7439945
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7434632
Quantity 100 μL
Datasheet Datasheet

Recommended TNFRSF11A ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6960281
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970969
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970968
Quantity 96 tests
Datasheet Datasheet

Recommended TNFRSF11A Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275521
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275522
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293T Cells
Validations
  • (2)
Cat. No. ABIN1323151
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our TNFRSF11A products

Hiyama, Yokoi, Akagi, Kadoyama, Nakamori, Tsuga, Uchida, Terayama: "Osteoclastogenesis from bone marrow cells during estrogen-induced medullary bone formation in Japanese quails." in: Journal of molecular histology, Vol. 50, Issue 4, pp. 389-404, (2019) (PubMed).

Ferguson, Wilcock, McEntegart, Badrock, Levesque, Dummer, Wellbrock, Smith: "Osteoblasts contribute to a protective niche that supports melanoma cell proliferation and survival." in: Pigment cell & melanoma research, (2019) (PubMed).

Wang, Song, Che, Zhang, Wang, Zhang, Qu, Li, Xu, Zhang, Fan, Hou, Liu, Qu: "Caveolin‑1 enhances RANKL‑induced gastric cancer cell migration." in: Oncology reports, Vol. 40, Issue 3, pp. 1287-1296, (2018) (PubMed).

Widowati, Afifah, Mozef, Sandra, Rizal, Amalia, Arinta, Bachtiar, Murti: "Effects of insulin-like growth factor-induced Wharton jelly mesenchymal stem cells toward chondrogenesis in an osteoarthritis model." in: Iranian journal of basic medical sciences, Vol. 21, Issue 7, pp. 745-752, (2018) (PubMed).

Watari, Shibata, Nabeshima, Shinoda, Fukunaga, Kawahara, Karasuyama, Fukushi, Iwamoto, Kuwano, Ono: "Impaired differentiation of macrophage lineage cells attenuates bone remodeling and inflammatory angiogenesis in Ndrg1 deficient mice." in: Scientific reports, Vol. 6, pp. 19470, (2016) (PubMed).

Nanke, Kobashigawa, Yago, Kawamoto, Yamanaka, Kotake: "RANK Expression and Osteoclastogenesis in Human Monocytes in Peripheral Blood from Rheumatoid Arthritis Patients." in: BioMed research international, Vol. 2016, pp. 4874195, (2016) (PubMed).

Huynh, VonMoss, Smith, Rahman, Felemban, Zuo, Rody, McHugh, Holliday: "Characterization of Regulatory Extracellular Vesicles from Osteoclasts." in: Journal of dental research, Vol. 95, Issue 6, pp. 673-9, (2016) (PubMed).

Kunt, Şentürk, Gönül, Korkmaz, Ahsen, Hazman, Bal, Genç, Songur: "Effects of electromagnetic radiation exposure on bone mineral density, thyroid, and oxidative stress index in electrical workers." in: OncoTargets and therapy, Vol. 9, pp. 745-54, (2016) (PubMed).

Chypre, Seaman, Cordeiro, Willen, Knoop, Buchanan, Sainson, Williams, Yagita, Schneider, Mueller: "Characterization and application of two RANK-specific antibodies with different biological activities." in: Immunology letters, Vol. 171, pp. 5-14, (2016) (PubMed).

Kaneko, Ota, Nakashima, Nagasaki, Kodani, Mori, Nagatsu: "Lipopolysaccharide treatment arrests the cell cycle of BV-2 microglial cells in G₁ phase and protects them from UV light-induced apoptosis." in: Journal of neural transmission (Vienna, Austria : 1996), Vol. 122, Issue 2, pp. 187-99, (2015) (PubMed).

Synonyms and alternative names related to TNFRSF11A

TNF receptor superfamily member 11A (Tnfrsf11a), TNF receptor superfamily member 11a (TNFRSF11A), tumor necrosis factor receptor superfamily, member 11a, NFKB activator (Tnfrsf11a), CD265, FEO, LOH18CR1, Ly109, mRANK, ODFR, OFE, OPTB7, OSTS, PDB2, RANK, Rank, RGD1563614, TNFRSF11A, TRANCE-R, TRANCER

Protein level used designations for TNFRSF11A

  • tumor necrosis factor receptor superfamily member 11A
  • tumor necrosis factor receptor superfamily, member 11a, NFKB activator
  • receptor activator of nuclear factor-kappa B
  • tumor necrosis factor receptor superfamily member 11A-like
  • osteoclast differentiation factor receptor
  • receptor activator of NF-KB
  • receptor activator of NF-kappaB
  • loss of heterozygosity, 18, chromosomal region 1
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