PPARGC1B antibody (AA 195-414)

Catalog No. ABIN2683008

Product Details anti-PPARGC1B Antibody

Target: PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Binding Specificity: AA 195-414

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PPARGC1B antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: PPARGC1B Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human PPARGC1B (AA: 195-414) expressed in E. Coli.

Clone: 6C3F6

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for PPARGC1B

Target: PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Alternative Name: PPARGC1B (PPARGC1B Products)

Background:

Description: The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.

Aliases: PERC, ERRL1, PGC1B, PGC-1(beta)

Molecular Weight: 113.2kDa

Gene ID: 133522

HGNC: 133522

UniProt: Q86YN6

Pathways: AMPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha