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PPARGC1B antibody (AA 901-1023)

PPARGC1B Reactivity: Human WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN872354
  • Target See all PPARGC1B Antibodies
    PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))
    Binding Specificity
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 901-1023
    Reactivity
    • 34
    • 8
    • 2
    Human
    Host
    • 32
    • 2
    Rabbit
    Clonality
    • 22
    • 12
    Polyclonal
    Conjugate
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPARGC1B antibody is un-conjugated
    Application
    • 25
    • 12
    • 12
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Pig,Rabbit,Guinea Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PGC1 beta
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Zhou, Ma, Mo, Zheng, Chen, Wei, Dai et al.: "Down-regulating peroxisome proliferator-activated receptor-gamma coactivator-1 beta alleviates the proinflammatory effect of rheumatoid arthritis fibroblast-like synoviocytes through inhibiting ..." in: Arthritis research & therapy, Vol. 16, Issue 5, pp. 472, (2015) (PubMed).

  • Target
    PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))
    Alternative Name
    PGC1 beta (PPARGC1B Products)
    Synonyms
    PPARGC1B antibody, 4631412G21Rik antibody, Perc antibody, PGC1beta antibody, ERRL1 antibody, PERC antibody, PGC-1(beta) antibody, PGC1B antibody, PPARG coactivator 1 beta antibody, peroxisome proliferative activated receptor, gamma, coactivator 1 beta antibody, PPARGC1B antibody, Ppargc1b antibody
    Background

    Synonyms: PERC, peroxisome prolerative activated receptor, gamma, coactivator 1, peroxisome prolerator-activated receptor gamma coactivator 1 beta, Peroxisome prolerator-activated receptor gamma coactivator 1-beta, peroxisome prolerator-activated receptor gamma, coactivator 1 beta, PGC-1beta, PGC-1-beta, PGC-1-related estrogen receptor alpha coactivator, PGC1, PPAR gamma coactivator-1beta, PPAR-gamma coactivator 1-beta, PPARGC-1-beta, PPARGC1, Ppargc1b, PRGC2_HUMAN.

    Background: Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure.Tissue specificity: Ubiquitous with higher expression in heart, brain and skeletal muscle.

    Molecular Weight
    113kDa
    Gene ID
    133522
    Pathways
    AMPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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