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PDE4C antibody (C-Term)

PDE4C Reactivity: Human, Mouse, Rat WB, ELISA, IF, IP, IHC, ICC, CM Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2750931
  • Target See all PDE4C Antibodies
    PDE4C (phosphodiesterase 4C, CAMP-Specific (PDE4C))
    Binding Specificity
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 31
    • 11
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 28
    • 3
    Rabbit
    Clonality
    • 29
    • 2
    Polyclonal
    Conjugate
    • 19
    • 3
    • 3
    • 2
    • 2
    • 2
    This PDE4C antibody is un-conjugated
    Application
    • 31
    • 22
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Confocal Microscopy (CM)
    Purification
    Affinity Purified
    Immunogen
    Synthetic cyclic carboxy-terminal peptide common to all PDE4C variants.
    Isotype
    IgG
    Top Product
    Discover our top product PDE4C Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.65 μg/μL
  • Cheng, Wu, He, Liu, Jia, Di, Ji: "siRNA-mediated silencing of phosphodiesterase 4B expression affects the production of cytokines in endotoxin-stimulated primary cultured microglia." in: Experimental and therapeutic medicine, Vol. 12, Issue 4, pp. 2257-2264, (2017) (PubMed).

    Ji, Di, He, Liu, Liu, Li, Zhang: "Intrathecal injection of phosphodiesterase 4B-specific siRNA attenuates neuropathic pain in rats with L5 spinal nerve ligation." in: Molecular medicine reports, Vol. 13, Issue 2, pp. 1914-22, (2016) (PubMed).

    Massimi, Cardarelli, Galli, Giardi, Ragusa, Panera, Cinque, Cifone, Biagioni, Giorgi: "Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival." in: Journal of cellular biochemistry, Vol. 118, Issue 6, pp. 1401-1411, (2016) (PubMed).

    Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

    Yougbaré, Boire, Roy, Lugnier, Rouseau: "NCS 613 exhibits anti-inflammatory effects on PBMCs from lupus patients by inhibiting p38 MAPK and NF-κB signalling pathways while reducing proinflammatory cytokine production." in: Canadian journal of physiology and pharmacology, Vol. 91, Issue 5, pp. 353-61, (2014) (PubMed).

    Abusnina, Alhosin, Keravis, Muller, Fuhrmann, Bronner, Lugnier: "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." in: Cellular signalling, Vol. 23, Issue 1, pp. 152-60, (2011) (PubMed).

    Yougbare, Morin, Senouvo, Sirois, Albadine, Lugnier, Rousseau: "NCS 613, a potent and specific PDE4 inhibitor, displays anti-inflammatory effects on human lung tissues." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 301, Issue 4, pp. L441-50, (2011) (PubMed).

    Murray, Patel, Suda, Zhang, Thistlethwaite, Yuan, Insel: "Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: role for PDE1." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 292, Issue 1, pp. L294-303, (2007) (PubMed).

    Gallagher, Bacon, Odumeru, Gallagher, Fitzpatrick, Regan: "Valproate activates phosphodiesterase-mediated cAMP degradation: relevance to C6 glioma G1 phase progression." in: Neurotoxicology and teratology, Vol. 26, Issue 1, pp. 73-81, (2004) (PubMed).

  • Target
    PDE4C (phosphodiesterase 4C, CAMP-Specific (PDE4C))
    Alternative Name
    PDE4C (PDE4C Products)
    Synonyms
    im:7160317 antibody, pde4c antibody, si:dkey-149i17.5 antibody, PDE4C antibody, dpde1 antibody, Dpde1 antibody, E130301F19Rik antibody, dunce antibody, DPDE1 antibody, phosphodiesterase 4C antibody, phosphodiesterase 4C, cAMP-specific a antibody, phosphodiesterase 4C, cAMP specific antibody, PDE4C antibody, pde4ca antibody, pde4c antibody, Pde4c antibody
    UniProt
    Q08493
    Pathways
    Negative Regulation of Hormone Secretion, cAMP Metabolic Process
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