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IL-5 antibody (Interleukin 5) (Middle Region) Primary Antibody

IL5 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2774069
$389.00
Plus shipping costs $45.00
100 μL
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  • Target
    IL-5 (IL5)
    Binding Specificity
    • 15
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 84
    • 56
    • 21
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 67
    • 37
    • 14
    • 2
    Rabbit
    Clonality
    • 68
    • 52
    Polyclonal
    Conjugate
    • 74
    • 17
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-5 antibody is un-conjugated
    Application
    • 70
    • 62
    • 24
    • 19
    • 18
    • 13
    • 13
    • 10
    • 9
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    LESQTVQGGT VERLFKNLSL IKKYIDGQKK KCGEERRRVN QFLDYLQEFL
    Predicted Reactivity
    Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against IL5. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human IL5
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 134 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    IL-5 (IL5)
    Alternative Name
    IL5 (IL5 Antibody Abstract)
    Synonyms
    EDF, IL-5, TRF, Il-5, IL5, interleukin 5, IL5, Il5
    Background
    IL5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. This cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The protein encoded by this gene is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. This cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of this cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. This cytokine, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: EDF, IL-5, TRF
    Protein Interaction Partner: CXCL8, IL5RA, IL5, STAT5A,
    Protein Size: 134
    Molecular Weight
    13 kDa
    Gene ID
    3567
    NCBI Accession
    NM_000879, NP_000870
    UniProt
    P05113
    Pathways
    JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
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