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Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 (KCNJ12) (Middle Region) antibody Primary Antibody

KCNJ12 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2776235
$389.00
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100 μL
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  • Target
    Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 (KCNJ12)
    Binding Specificity
    • 8
    • 8
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 23
    • 14
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse
    Host
    • 24
    • 5
    Rabbit
    Clonality
    • 24
    • 5
    Polyclonal
    Conjugate
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Un-conjugated
    Application
    • 27
    • 16
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    KDLVENKFLL PSANSFCYEN ELAFLSRDEE DEADGDQDGR SRDGLSPQAR
    Predicted Reactivity
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against KCNJ12. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human KCNJ12
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 433 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 (KCNJ12)
    Alternative Name
    KCNJ12 (KCNJ12 Antibody Abstract)
    Synonyms
    IRK-2, IRK2, KCNJN1, Kir2.2, Kir2.2v, hIRK, hIRK1, hkir2.2x, kcnj12x, Kir2.1, IRK, KIR2.2, MB-IRK2, potassium voltage-gated channel subfamily J member 12, ATP-sensitive inward rectifier potassium channel 12, potassium inwardly-rectifying channel, subfamily J, member 12, KCNJ12, LOC746628, Kcnj12
    Background
    KCNJ12 is an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current (IK1). This gene is located within the Smith-Magenis syndrome region on chromosome 17. This gene encodes an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current (IK1). The gene is located within the Smith-Magenis syndrome region on chromosome 17. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-486 BC027982.1 12-497 487-488 AC068418.5 101651-101652 489-2455 BC027982.1 500-2466 2456-2483 DA115102.1 132-159 2484-2485 AC068418.5 141899-141900 2486-2889 DA115102.1 161-564 2890-3454 BM799671.1 118-682 3455-3457 AC068418.5 142870-142872 3458-4692 AK024229.1 926-2160 4693-5230 AK024229.1 2163-2700
    Alias Symbols: FLJ14167, IRK2, KCNJN1, Kir2.2, Kir2.2v, hIRK, hIRK1, hkir2.2x, kcnj12x, IRK-2
    Protein Interaction Partner: UBC, LIN7C, LIN7B, DLG2, LIN7A, DLG4, APBA1, ABLIM1, PRKACA, DTNA, SNTA1, DLG1, SNTB2, SNTB1, DMD, DLG3, CASK, MPP6,
    Protein Size: 433
    Molecular Weight
    49 kDa
    Gene ID
    3768
    NCBI Accession
    NM_021012, NP_066292
    UniProt
    Q14500
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