Kir2.2 antibody (AA 182-433) (FITC)

Catalog No. ABIN7145027

Product Details anti-Kir2.2 Antibody (FITC)

Target: Kir2.2 (KCNJ12) (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 (KCNJ12))

Binding Specificity: AA 182-433

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kir2.2 antibody is conjugated to FITC

Application: Please inquire

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human ATP-sensitive inward rectifier potassium channel 12 protein (182-433aa)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Kir2.2

Target: Kir2.2 (KCNJ12) (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 (KCNJ12))

Alternative Name: KCNJ12 (KCNJ12 Products)

Synonyms: IRK-2 antibody, IRK2 antibody, KCNJN1 antibody, Kir2.2 antibody, Kir2.2v antibody, hIRK antibody, hIRK1 antibody, hkir2.2x antibody, kcnj12x antibody, Kir2.1 antibody, IRK antibody, KIR2.2 antibody, MB-IRK2 antibody, potassium voltage-gated channel subfamily J member 12 antibody, ATP-sensitive inward rectifier potassium channel 12 antibody, potassium inwardly-rectifying channel, subfamily J, member 12 antibody, KCNJ12 antibody, LOC746628 antibody, Kcnj12 antibody

Background:

Background: Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

Aliases: ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Inward rectifier K(+) channel Kir2.2v) (Potassium channel, inwardly rectifying subfamily J member 12), KCNJ12, IRK2 KCNJN1

UniProt: Q14500