Cystatin S (CST4) (N-Term) antibody

Details for Product No. ABIN2777098
Antigen
Epitope
N-Term
16
6
3
Reactivity
Human
81
10
2
Host
Rabbit
51
30
Clonality
Polyclonal
Conjugate
Un-conjugated
7
6
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
43
14
14
13
8
8
7
7
5
3
2
2
1
1
Options
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human CST4
Sequence MARPLCTLLL LMATLAGALA SSSKEENRII PGGIYDADLN DEWVQRALHF
Predicted Reactivity Human: 100%
Characteristics This is a rabbit polyclonal antibody against CST4. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Antigen
Alternative Name CST4 (CST4 Antibody Abstract)
Background The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The protein is an S-type cystatin, based on its high level of expression in saliva, tears and seminal plasma. The specific role in these fluids is unclear but antibacterial and antiviral activity is present, consistent with a protective function.The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a type 2 salivary cysteine peptidase inhibitor. The protein is an S-type cystatin, based on its high level of expression in saliva, tears and seminal plasma. The specific role in these fluids is unclear but antibacterial and antiviral activity is present, consistent with a protective function.
Alias Symbols: MGC71923
Protein Interaction Partner: UBC,
Protein Size: 141
Molecular Weight 16 kDa
Gene ID 1472
NCBI Accession NM_001899, NP_001890
UniProt P01036
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 141 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Image no. 1 for anti-Cystatin S (CST4) (N-Term) antibody (ABIN2777098) WB Suggested Anti-CST4 Antibody Titration: 1.25ug/ml Positive Control: HepG2 cell ...