SHQ1 antibody (N-Term)

Catalog No. ABIN2787069

Product Details anti-SHQ1 Antibody

Target: SHQ1 (SHQ1 Homolog (SHQ1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Saccharomyces cerevisiae, Cow, Dog, Guinea Pig, Horse, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHQ1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PYFLRLTLPG RIVENGSEQG TYDADKGIFT IRLPKETPGQ HFEGLNMLTA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%

Characteristics: This is a rabbit polyclonal antibody against Shq1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Shq1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 458 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SHQ1

Target: SHQ1 (SHQ1 Homolog (SHQ1))

Alternative Name: Shq1 (SHQ1 Products)

Background: Shq1 is required for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs), including telomerase, probably through the stabilization of DKC1, from the time of its synthesis until its association with NOP10, NHP2, and NAF1 at the nascent H/ACA RNA.
Alias Symbols: 2810403P18Rik, Grim-1
Protein Size: 458

Molecular Weight: 50 kDa

Gene ID: 72171

NCBI Accession: NM_181590, NP_853621

Pathways: Ribonucleoprotein Complex Subunit Organization