RAP1 antibody (Middle Region)

Catalog No. ABIN2787164

Product Details anti-RAP1 Antibody

Target: RAP1 (TERF2IP) (Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EDPEAADSGE PQNKRTPDLP EEEYVKEEIQ ENEEAVKKML VEATREFEEV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against TERF2IP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TERF2IP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 399 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RAP1

Target: RAP1 (TERF2IP) (Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP))

Alternative Name: TERF2IP (TERF2IP Products)

Background: The gene encodes a protein that is part of a complex involved in telomere length regulation. Pseudogenes are present on chromosomes 5 and 22.
Alias Symbols: DRIP5, RAP1
Protein Interaction Partner: TERF2, UBC, ANXA8L1, WDR92, PANK4, PPP2R5E, RIF1, RAD50, NBN, MRE11A, SLX4, TFAP4, LANCL2, ENAH, PPP6R3, MAGOHB, BANP, RPP25, EPS8L1, C9orf78, SCLY, MRTO4, SBDS, HDGFRP3, PACSIN3, LGALSL, BABAM1, DBNL, GPKOW, GNMT, WIPI2, TOR1AIP1, RPAP1, CHMP2B, PGLS, HA
Protein Size: 399

Molecular Weight: 44 kDa

Gene ID: 54386

NCBI Accession: NM_018975, NP_061848

UniProt: Q9NYB0

Pathways: Cell Division Cycle, Telomere Maintenance