MMAA antibody (N-Term)

Catalog No. ABIN2789699

Product Details anti-MMAA Antibody

Target: MMAA (Methylmalonic Aciduria (Cobalamin Deficiency) Type A (MMAA))

Binding Specificity: N-Term

Reactivity: Human, Rat, Horse, Rabbit, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMAA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GQRACLAEAI TLVESTHSRK KELAQVLLQK VLLYHREQEQ SNKGKPLAFR

Predicted Reactivity: Cow: 85%, Dog: 86%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Rabbit: 93%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against MMAA. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 418 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MMAA

Target: MMAA (Methylmalonic Aciduria (Cobalamin Deficiency) Type A (MMAA))

Alternative Name: MMAA (MMAA Products)

Synonyms: 2810018E08Rik antibody, AI840684 antibody, cblA antibody, methylmalonic aciduria (cobalamin deficiency) type A antibody, methylmalonic aciduria (cobalamin deficiency) cblA type antibody, Mmaa antibody, MMAA antibody

Background: The protein encoded by this gene is involved in the translocation of cobalamin into the mitochondrion, where it is used in the final steps of adenosylcobalamin synthesis. Adenosylcobalamin is a coenzyme required for the activity of methylmalonyl-CoA mutase. Defects in this gene are a cause of methylmalonic aciduria.
Alias Symbols: MGC120010, MGC120011, MGC120012, MGC120013, cblA
Protein Interaction Partner: MMAA, MUT,
Protein Size: 418

Molecular Weight: 46 kDa

Gene ID: 166785

NCBI Accession: NM_172250, NP_758454

UniProt: Q8IVH4

Pathways: Monocarboxylic Acid Catabolic Process