KRT18 antibody (Keratin 18) (Internal Region)

Details for Product anti-KRT18 Antibody No. ABIN2856142
Antigen
  • CK18
  • K18
  • Krt1-18
  • CYK18
  • DreK18
  • cb83
  • dapk1
  • sb:cb83
  • wu:fa13f02
  • wu:fb36b04
  • krt18
  • MGC64569
  • MGC75922
  • KRT18
  • keratin 18
  • keratin 18, type I L homeolog
  • keratin 18, type I
  • keratin, type I cytoskeletal 18
  • K18, simple type I keratin
  • Keratin, type I cytoskeletal 18
  • Krt18
  • KRT18
  • krt18
  • krt18.L
  • LOC700569
  • LOC100136778
  • k1c18
  • LOC100008885
Epitope
Internal Region
34
33
26
17
16
15
11
9
8
8
7
7
5
5
4
4
4
4
4
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
882
225
215
126
95
64
64
52
48
37
35
33
33
33
24
14
11
9
6
3
2
2
2
1
1
Host
Rabbit
593
326
14
7
5
2
1
Clonality
Polyclonal
Conjugate
This KRT18 antibody is un-conjugated
55
41
18
11
11
11
11
11
11
10
9
9
8
8
8
8
8
8
8
8
8
8
8
8
8
8
3
3
3
3
3
2
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
562
398
367
365
240
193
170
85
77
76
41
40
30
17
14
11
2
1
1
1
Options
Immunogen Recombinant protein encompassing a sequence within the center region of human Cytokeratin 18. The exact sequence is proprietary.
Isotype IgG
Cross-Reactivity Mouse (Murine), Rat (Rattus), Cow (Bovine)
Cross-Reactivity (Details) Mouse (93 %), Rat (92 %), Bovine (92 %)
Characteristics Rabbit polyclonal antibody to Cytokeratin 18 (keratin 18)
Cytokeratin 18 antibody [N2C2], Internal
Purification Purified by antigen-affinity chromatography.
Plasmids, Primers & others Plasmids, Primers & others KRT18 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Cytokeratin 18 (KRT18 Antibody Abstract)
Background KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

Cellular Localization: Cytoplasm , perinuclear region
Molecular Weight 48 kDa
Gene ID 3875
Pathways Apoptosis, Caspase Cascade in Apoptosis
Application Notes Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
Comment

Positive Control: H1299 , HepG2

Restrictions For Research Use only
Format Liquid
Concentration 0.54 mg/mL
Buffer 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Supplier Images
Image no. 1 for anti-Keratin 18 (KRT18) (Internal Region) antibody (ABIN2856142) ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Cytoke...
Image no. 2 for anti-Keratin 18 (KRT18) (Internal Region) antibody (ABIN2856142) IHC-P Image Immunohistochemical analysis of paraffin-embedded human endo mitral ovari...
Image no. 3 for anti-Keratin 18 (KRT18) (Internal Region) antibody (ABIN2856142) ICC/IF Image Cytokeratin 18 antibody [N2C2], Internal detects Cytokeratin 18 protein ...
Image no. 4 for anti-Keratin 18 (KRT18) (Internal Region) antibody (ABIN2856142) WB Image Sample(30 μg of whole cell lysate) A:H1299 B:Hep G2, 7.5% SDS PAGE antibody ...