AP1S2 antibody (full length)

Catalog No. ABIN2856670

Product Details anti-AP1S2 Antibody

Target: AP1S2 (Adaptor-Related Protein Complex 1, sigma 2 Subunit (AP1S2))

Binding Specificity: full length

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP1S2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Cross-Reactivity: Rat (Rattus), Chimpanzee

Cross-Reactivity (Details): Rat (100 %), Chimpanzee (100 %)

Characteristics: Rabbit Polyclonal antibody to AP1S2 (adaptor-related protein complex 1, sigma 2 subunit)
AP1S2 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Full length human AP1S2 Recombinant protein.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: A431 , Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.53 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for AP1S2

Target: AP1S2 (Adaptor-Related Protein Complex 1, sigma 2 Subunit (AP1S2))

Alternative Name: AP1S2 (AP1S2 Products)

Background: Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants utilizing alternative polyadenylation signals exist for this gene.

Cellular Localization: Golgi apparatus , Cytoplasmic vesicle membrane , Membrane , clathrin-coated pit

Molecular Weight: 19 kDa

Gene ID: 8905