AP1S2 antibody (C-Term)

Catalog No. ABIN5515778

The Rabbit Polyclonal anti-AP1S2 antibody (ABIN5515778) specifically detects AP1S2 in WB. The antibody is reactive with Human samples.

Quick Overview for AP1S2 antibody (C-Term) (ABIN5515778)

Target: AP1S2 (Adaptor-Related Protein Complex 1, sigma 2 Subunit (AP1S2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP1S2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AP1S2 Antibody

Binding Specificity: C-Term

Purpose: AP1S2 Antibody - C-terminal region

Sequence: YFGSVCELDI IFNFEKAYFI LDEFLLGGEV QETSKKNVLK AIEQADLLQE

Characteristics: This is a rabbit polyclonal antibody against AP1S2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human AP1S2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP73908-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for AP1S2

Target: AP1S2 (Adaptor-Related Protein Complex 1, sigma 2 Subunit (AP1S2))

Alternative Name: AP1S2

Background:

Background Information: Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants encoding different isoforms have been found for this gene.

Alternative Symbols: PGS, DC22, MRX59, MRXS5, MRXSF, MRXS21, SIGMA1B

Molecular Weight: 17kDa

Gene ID: 8905

UniProt: P56377