Endonuclease G antibody (AA 49-297)

Catalog No. ABIN1679714

Product Details anti-Endonuclease G Antibody

Target: Endonuclease G (ENDOG)

Binding Specificity: AA 49-297

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Endonuclease G antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AELPPVPGGP RGPGELAKYG LPGLAQLKSR ESYVLCYDPR TRGALWVVEQ LRPERLRGDG DRRECDFRED DSVHAYHRAT NADYRGSGFD RGHLAAAANH RWSQKAMDDT FYLSNVAPQV PHLNQNAWNN LEKYSRSLTR SYQNVYVCTG PLFLPRTEAD GKSYVKYQVI GKNHVAVPTH FFKVLILEAA GGQIELRTYV MPNAPVDEAI PLERFLVPIE SIERASGLLF VPNILARAGS LKAITAGSK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 49-297 of human Endo G (NP_004426.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Endonuclease G

Target: Endonuclease G (ENDOG)

Alternative Name: ENDOG (ENDOG Products)

Background: The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.,ENDOG,Epigenetics & Nuclear Signaling,Cancer,Invasion and Metastasis,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Cell Cycle,Endocrine & Metabolism,Mitochondrial metabolism,ENDOG

Molecular Weight: 32 kDa

Gene ID: 2021

UniProt: Q14249

Pathways: Apoptosis