Pkc beta 1 antibody (AA 542-671)
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- Target See all Pkc beta 1 Antibodies
- Pkc beta 1 (Protein Kinase C, beta 1 (Pkc beta 1))
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Binding Specificity
- AA 542-671
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Reactivity
- Rat, Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Pkc beta 1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Antigen affinity
- Immunogen
- Human partial recombinant protein (AA 542-671) was used as the immunogen for this PKC beta antibody.
- Isotype
- IgG
- Top Product
- Discover our top product Pkc beta 1 Primary Antibody
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- Application Notes
- The stated application concentrations are suggested starting amounts. Titration of the PKC beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Storage
- -20 °C
- Storage Comment
- After reconstitution, the PKC beta antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Target
- Pkc beta 1 (Protein Kinase C, beta 1 (Pkc beta 1))
- Alternative Name
- PKC beta 1 (Pkc beta 1 Products)
- Background
- Protein kinase C beta type is an enzyme that in humans is encoded by the PRKCB gene. It is a member of the protein kinase C (PKC) gene family. Family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. Family members also serve as major receptors for phorbol esters, a class of tumor promoters. PKC beta has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. It has been found that it is activated by oxidative conditions in the cell, induces phosphorylation of < a href=../search_result.php?search_txt=shc>p66 (SHC) and triggers mitochondrial accumulation of the protein after it is recognized by the prolyl isomerase < a href=../search_result.php?search_txt=pin1>PIN1.
- Gene ID
- 5579
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