Pkc beta 1 antibody (N-Term)

Catalog No. ABIN2786693

Cited in 1 publication. The Rabbit Polyclonal anti-Pkc beta 1 antibody (ABIN2786693) specifically detects Pkc beta 1 in WB. The antibody is reactive with Human, Rat, Mouse, Rabbit, Cow and Pig samples.

Quick Overview for Pkc beta 1 antibody (N-Term) (ABIN2786693)

Target: Pkc beta 1 (Protein Kinase C, beta 1 (Pkc beta 1))

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pkc beta 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Pkc beta 1 Antibody

Binding Specificity: N-Term

Purpose: PRKCB1 Antibody - N-terminal region

Sequence: MADPAAGPPP SEGEESTVRF ARKGALRQKN VHEVKNHKFT ARFFKQPTFC

Predicted Reactivity: Cow: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PRKCB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRKCB1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56423-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-Pkc beta 1 antibody (ABIN2786693)

Tatematsu, Yoshimoto, Okajima, Tanizawa, Kuroda: "Identification of ubiquitin ligase activity of RBCK1 and its inhibition by splice variant RBCK2 and protein kinase Cbeta." in: The Journal of biological chemistry, Vol. 283, Issue 17, pp. 11575-85, (2008) (PubMed).

Target Details for Pkc beta 1

Target: Pkc beta 1 (Protein Kinase C, beta 1 (Pkc beta 1))

Alternative Name: PRKCB1

Background:

Background Information: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in d

Gene Name: Protein kinase C, beta

Alternative Symbols: PKCB, PRKCB1, PRKCB2, PKCI(2), PKCbeta, PKC-beta

Protein Name: Protein kinase C beta type

Molecular Weight: 77kDa

Gene ID: 5579

NCBI Accession: NP_002729

UniProt: P05771