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Kallikrein 10 antibody (KLK10) (AA 252-265) Primary Antibody

KLK10 Reactivity: Human WB Host: Rabbit Polyclonal
Catalog No. ABIN3043037
$240.00
Plus shipping costs $45.00
100 μg
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  • Target
    Binding Specificity
    AA 252-265, C-Term
    Reactivity
    Human
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    This Kallikrein 10 antibody is un-conjugated
    Application
    Western Blotting (WB)
    Purpose
    Rabbit IgG polyclonal antibody for Kallikrein-10(KLK10) detection. Tested with WB in Human.
    Sequence
    SAQHPAVYTQ ICKY
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Kallikrein-10(KLK10) detection. Tested with WB in Human.
    Gene Name: kallikrein-related peptidase 10
    Protein Name: Kallikrein-10
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human Kallikrein 10(252-265aa SAQHPAVYTQICKY).
    Isotype
    IgG
  • Target
    Alternative Name
    KLK10 (KLK10 Antibody Abstract)
    Background
    KLK10(kallikrein-related peptidase 10) also known as kallikrein 10, PRSSL1 or NES1, belongs to the kallikrein subfamily of serine proteases, which are involved in a variety of enzymatic processes. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers.KLK10 also contains 12 conserved cysteines in its protease domain that are expected to form 6 disulfide bonds, as in other serine proteases. RT-PCR detected variable levels of KLK10 expression in nearly all of the 35 adult and fetal tissues examined. The KLK10 gene contains 6 exons, the first of which is noncoding. By fluorescence in situ hybridization, Polikoff et al.(1997) mapped the PRSSL1 gene to 19q13.3. By genomic sequence analysis, Gan et al.(2000) mapped the KLK10 gene within the KLK gene cluster on chromosome 19q13. This cluster includes 13 KLK genes and 5 pseudogenes.

    Synonyms: breast normal epithelial cell associated serine protease antibody|Kallikrein related peptidase 10 antibody|Kallikrein10 antibody|KLK 10 antibody|KLK10 antibody|NES 1 antibody|NES1 antibody|Normal epithelial cell specific 1 antibody|Protease serine like 1 antibody|PRSS L1 antibody|PRSSL 1 antibody|PRSSL1 antibody
    UniProt
    O43240
    Pathways
    Complement System
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Preservative
    Thimerosal (Merthiolate), Sodium azide
    Precaution of Use
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Expiry Date
    12 months
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