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CD59 antibody (AA 26-102)

CD59 Reactivity: Human FACS, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3043396
  • Target See all CD59 Antibodies
    CD59
    Binding Specificity
    • 16
    • 10
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 26-102
    Reactivity
    • 143
    • 14
    • 9
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 87
    • 75
    • 6
    • 6
    Rabbit
    Clonality
    • 96
    • 75
    • 1
    Polyclonal
    Conjugate
    • 82
    • 20
    • 14
    • 13
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD59 antibody is un-conjugated
    Application
    • 99
    • 72
    • 49
    • 41
    • 35
    • 28
    • 25
    • 17
    • 14
    • 14
    • 13
    • 13
    • 11
    • 11
    • 8
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Rabbit IgG polyclonal antibody for CD59 glycoprotein(CD59) detection. Tested with IHC-P, FCM in Human.
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for CD59 glycoprotein(CD59) detection. Tested with IHC-P, FCM in Human.
    Gene Name: CD59 Molecule, complement regulatory protein
    Protein Name: CD59 glycoprotein
    Purification
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human CD59 recombinant protein (Position: L26-N102). Human CD59 shares 47.1% amino acid (aa) sequence identity with rat CD59.
    Isotype
    IgG
    Top Product
    Discover our top product CD59 Primary Antibody
  • Application Notes
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Flow Cytometry: Concentration:1-3 μg/1x106 cells, Tested Species: Human
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    CD59
    Alternative Name
    CD59 (CD59 Products)
    Background
    This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. And this protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. It also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

    Synonyms: 16.3A5 antibody|1F5 antibody|1F5 antigen antibody|20 kDa homologous restriction factor antibody|CD 59 antibody|CD_antigen=CD59 antibody|CD59 antibody|CD59 antigen antibody|CD59 antigen complement regulatory protein antibody|CD59 antigen p18 20 antibody|CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) antibody|CD59 glycoprotein antibody|CD59 Molecule antibody|CD59 Molecule complement regulatory protein antibody|CD59_HUMAN antibody|Cd59a antibody|Complement regulatory protein antibody|EJ16 antibody|EJ30 antibody|EL32 antibody|FLJ38134 antibody|FLJ92039 antibody|G344 antibody|HRF 20 antibody|HRF-20 antibody|HRF20 antibody|Human leukocyte antigen MIC11 antibody|Ly 6 like protein antibody|Lymphocytic antigen CD59/MEM43 antibody| MAC inhibitory protein antibody|MAC IP antibody|MAC-inhibitory protein antibody|MAC-IP antibody|MACIF antibody|MACIP antibody|MEM43 antibody|MEM43 antigen antibody|Membrane attack complex (MAC) inhibition factor antibody|Membrane attack complex inhibition factor antibody|Membrane inhibitor of reactive lysis antibody|MGC2354 antibody|MIC11 antibody|MIN1 antibody|MIN2 antibody|MIN3 antibody|MIRL antibody|MSK21 antibody|p18 20 antibody| Protectin antibody|Surface antigen recognized by monoclonal antibody| 16.3A5 antibody|T cell activating protein antibody
    Gene ID
    966
    UniProt
    P13987
    Pathways
    Complement System
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