CD59 antibody (AA 26-102)
-
- Target See all CD59 Antibodies
- CD59
-
Binding Specificity
- AA 26-102
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This CD59 antibody is un-conjugated
-
Application
- Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Rabbit IgG polyclonal antibody for CD59 glycoprotein(CD59) detection. Tested with IHC-P, FCM in Human.
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
-
Rabbit IgG polyclonal antibody for CD59 glycoprotein(CD59) detection. Tested with IHC-P, FCM in Human.
Gene Name: CD59 Molecule, complement regulatory protein
Protein Name: CD59 glycoprotein - Purification
- Immunogen affinity purified.
- Immunogen
- E.coli-derived human CD59 recombinant protein (Position: L26-N102). Human CD59 shares 47.1% amino acid (aa) sequence identity with rat CD59.
- Isotype
- IgG
- Top Product
- Discover our top product CD59 Primary Antibody
-
-
- Application Notes
-
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Flow Cytometry: Concentration:1-3 μg/1x106 cells, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
-
Antibody can be supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
-
- Target
- CD59
- Alternative Name
- CD59 (CD59 Products)
- Background
-
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. And this protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. It also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
Synonyms: 16.3A5 antibody|1F5 antibody|1F5 antigen antibody|20 kDa homologous restriction factor antibody|CD 59 antibody|CD_antigen=CD59 antibody|CD59 antibody|CD59 antigen antibody|CD59 antigen complement regulatory protein antibody|CD59 antigen p18 20 antibody|CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) antibody|CD59 glycoprotein antibody|CD59 Molecule antibody|CD59 Molecule complement regulatory protein antibody|CD59_HUMAN antibody|Cd59a antibody|Complement regulatory protein antibody|EJ16 antibody|EJ30 antibody|EL32 antibody|FLJ38134 antibody|FLJ92039 antibody|G344 antibody|HRF 20 antibody|HRF-20 antibody|HRF20 antibody|Human leukocyte antigen MIC11 antibody|Ly 6 like protein antibody|Lymphocytic antigen CD59/MEM43 antibody| MAC inhibitory protein antibody|MAC IP antibody|MAC-inhibitory protein antibody|MAC-IP antibody|MACIF antibody|MACIP antibody|MEM43 antibody|MEM43 antigen antibody|Membrane attack complex (MAC) inhibition factor antibody|Membrane attack complex inhibition factor antibody|Membrane inhibitor of reactive lysis antibody|MGC2354 antibody|MIC11 antibody|MIN1 antibody|MIN2 antibody|MIN3 antibody|MIRL antibody|MSK21 antibody|p18 20 antibody| Protectin antibody|Surface antigen recognized by monoclonal antibody| 16.3A5 antibody|T cell activating protein antibody - Gene ID
- 966
- UniProt
- P13987
- Pathways
- Complement System
-