EPM2A antibody (Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin)) (AA 243-331)

Details for Product anti-EPM2A Antibody No. ABIN336090
Antigen
Epitope
AA 243-331
55
23
16
16
5
4
4
3
2
2
2
1
1
Reactivity
Human
138
14
12
6
4
3
3
2
2
Host
Mouse
71
63
7
Clonality (Clone)
Monoclonal ()
Conjugate
This EPM2A antibody is un-conjugated
8
8
8
7
7
7
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
119
72
44
32
29
9
4
3
2
2
2
1
1
1
1
Options
Immunogen Recombinant human EPM2A (aa 243-331) purified from E. coli
Clone K2A3
Isotype IgG1
Specificity The antibody recognizes EPM2A.
Cross-Reactivity (Details) Species reactivity (tested):Human
Characteristics Synonyms: EPM2A, Laforin, EC=3.1.3.48, EC=3.1.3.16, Lafora PTPase, LAFPTPase
Purification Protein-G affinity chromatography
Antigen
Alternative Name Laforin (EPM2A Antibody Abstract)
Background Epilepsy, progressive myoclonus type 2A (EPM2A), also known as laforin, is a dual-specificity phosphatase that associates with polyribosomes. The protein may be involved in the control of glycogen metabolism, particularly in monitoring for and preventing the formation of poorly branched glycogen molecules. Defects in EPM2A are a cause of progressive myoclonic epilepsy type 2(EPM2), also known as Lafora disease. EPM2 is an autosomal recessive and severe form of adolescent-onset progressive epilepsy.Synonyms: EC=3.1.3.16, EC=3.1.3.48, EPM2A, LAFPTPase, Lafora PTPase, Laforin
Gene ID 7957
UniProt O95278
Pathways Cellular Glucan Metabolic Process
Application Notes ELISA. Western blot (1: 1,000 - 1: 2,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4, containing 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
Image no. 1 for anti-Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A) (AA 243-331) antibody (ABIN336090) anti-Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A) (AA 243-331) antibody (Image 1)
Image no. 2 for anti-Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A) (AA 243-331) antibody (ABIN336090) anti-Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A) (AA 243-331) antibody (Image 2)