EPM2A antibody (Internal Region) (Biotin)

Catalog No. ABIN5539824

Product Details anti-EPM2A Antibody (Biotin)

Target: EPM2A (Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A))

Binding Specificity: Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This EPM2A antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purpose: Laforin (isoform a), Biotinylated

Sequence: EATGHTNEMK HTTD.

Specificity: This antibody is expected to recognize isoform a (NP_005661.1) only.

Cross-Reactivity: Cow, Dog, Human, Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Grade: Verified

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 38 kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 37.2 kDa according to NP_005661.1). See non-biotinylated parental product's datasheet for further QC data. Recommended concentration: 1-3 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:16000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for EPM2A

Target: EPM2A (Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A))

Alternative Name: EPM2A (EPM2A Products)

Synonyms: TG-B antibody, Tg(TcraK,TcrbK)TG-BFlv antibody, EPM2 antibody, MELF antibody, laforin antibody, EPM2A, laforin glucan phosphatase antibody, epilepsy, progressive myoclonic epilepsy, type 2 gene alpha antibody, EPM2A antibody, Epm2a antibody

Background: EPM2A, epilepsy, progressive myoclonus type 2A, Lafora disease (laforin), EPM2, MELF, LAFPTPase, epilepsy, progressive myoclonus type 2, Lafora disease (laforin), glucan phosphatase, lafora PTPase

Gene ID: 7957, 13853, 680683

NCBI Accession: NP_005661

Pathways: Cellular Glucan Metabolic Process