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GATA1 antibody (GATA Binding Protein 1 (Globin Transcription Factor 1)) (Internal Region) Primary Antibody

GATA1 Reactivity: Human WB Host: Goat Polyclonal unconjugated
Catalog No. ABIN374593
$537.90
Plus shipping costs $45.00
0.1 mg
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Available
  • Target
    GATA1
    Binding Specificity
    • 26
    • 23
    • 16
    • 9
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 111
    • 56
    • 35
    • 13
    • 8
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    Human
    Host
    • 114
    • 9
    • 8
    Goat
    Clonality
    • 114
    • 16
    Polyclonal
    Conjugate
    • 67
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    This GATA1 antibody is un-conjugated
    Application
    • 84
    • 46
    • 40
    • 39
    • 26
    • 22
    • 19
    • 17
    • 14
    • 10
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    This antibody reacts to GATA1.
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Rat, Canine, Bovine.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Immunogen
    Peptide with sequence C-DAEAYRHSPVFQ, from the internal region of the protein sequence
  • Application Notes
    Peptide ELISA: 1/16000. Western Blot: 0.3 - 1.0 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0,5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    GATA1
    Alternative Name
    GATA1 (GATA1 Antibody Abstract)
    Synonyms
    ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT, Gata-1, Gf-1, eryf1, Eryf1, GATA1, gata-1, Gata1, si:dkeyp-77f7.5, XGATA-1B, gata1b-A, xGATA-1, xgata1, gata1, gta1, zg1, NF-E1a, GATA binding protein 1, GATA binding protein 1 (globin transcription factor 1), amidase, aspartyl/glutamyl-tRNA amidotransferase subunit A, putative amidase, GatA1, glutamyl-tRNA amidotransferase subunit A, hematopietic transcription factor GATA-1, GATA binding protein 1b, GATA binding protein 1 S homeolog, GATA binding protein 1a, erythroid transcription factor, GATA1, Gata1, gatA1, gata-1, gata1b, gata1.S, gata1a, LOC108348091
    Background
    GATA1 (Globin transcription factor 1) is a Cys2/Cys2 zinc finger DNA binding protein that is expressed primarily in erythroid, megakaryocytic, mast cells and eosinophilic cells. It belongs to the GATA family of transcription factors. GATA1 is a transcriptional activator which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence [AT]GATA[AG] within regulatory regions of globin genes and of other genes expressed in erythroid cells. The protein also plays an important role in erythroid development by regulating the switch from fetal hemoglobin production to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. Acquired somatic mutations in GATA1 occur in virtually all children with Down's Syndrome, congenital transient myeloproliferative syndrome (TMD) and acute megakaryocytic leukemia.Synonyms: ERYF1, Eryf1, Erythroid transcription factor, GATA-1, GATA-binding factor 1, GF-1, GF1, NF-E1 DNA-binding protein
    Gene ID
    2623
    NCBI Accession
    NP_002040
    UniProt
    P15976
    Pathways
    Cellular Response to Molecule of Bacterial Origin
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