Caspase 3 antibody (Caspase 3, Apoptosis-Related Cysteine Peptidase)

Details for Product anti-CASP3 Antibody No. ABIN379634
Antigen
  • CPP32
  • CPP32B
  • SCA-1
  • A830040C14Rik
  • AC-3
  • Apopain
  • CC3
  • Caspase-3
  • Lice
  • Yama
  • mldy
  • xcpp32
  • casp3
  • zgc:100890
  • CASP-3
  • caspase-3
  • caspase 3
  • caspase 3 S homeolog
  • caspase 3, apoptosis-related cysteine peptidase a
  • caspase 3, apoptosis-related cysteine peptidase
  • CASP3
  • Casp3
  • casp3.S
  • casp3a
Reactivity
Cow (Bovine), Dog (Canine), Hamster, Human, Monkey, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine)
548
324
268
43
26
24
21
21
17
12
12
11
8
7
4
4
3
2
2
Host
Rabbit
523
99
10
4
2
Clonality
Polyclonal
Conjugate
This Caspase 3 antibody is un-conjugated
35
25
18
12
11
11
10
10
10
10
9
9
3
2
2
2
2
2
2
1
1
Application
Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
463
251
207
100
61
56
53
49
36
29
22
15
10
9
7
2
1
1
1
Options
Immunogen Recombinant full-length human Caspase 3 protein.

Type of Immunogen: Recombinant protein
Specificity Reacts with active form of caspase 3 (17 kD protein). Caspase 3 is a member of the interleukin-1 beta-converting enzyme family. Caspase 3 is though to be associated with induction of apoptosis. Caspase 3 is synthesized as inactive 32 kD proenzyme and is processed during apoptosis generating two subunits of 17 kD and 12 kD. Caspase 3 stains the epithelial cells of skin, renal proximal tubules and collecting ducts. This antibody cross reacts with mouse, rat, monkey, rabbit, hamster, cow, sheep, pig and dog.
Purification Ig fraction
Plasmids, Primers & others Plasmids, Primers & others Caspase 3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name CASP3 / Caspase 3 (CASP3 Antibody Abstract)
Background Name/Gene ID: CASP3
Subfamily: Cysteine C14
Family: Protease

Synonyms: CASP3, Apopain, CASP-3, Caspase-3, CPP32B, CPP32, Cysteine protease CPP32, SCA-1, SREBP cleavage activity 1, Yama, Procaspase3, Caspase 3, CPP-32, PARP cleavage protease, Protein Yama
Gene ID 836
Pathways Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
Application Notes Approved: IHC, IHC-P (1:50 - 1:100)

Usage: FFPE tissue sections require high temperature antigen unmasking with 10 mM citrate buffer,  pH 6.0 prior to immunostaining.
Comment

Target Species of Antibody: Human

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Antiserum, sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze.
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