ABCG2 antibody (Center)
ABCG2
Reactivity: Human
WB, FACS, IF, IHC (p)
Host: Rabbit
Polyclonal
RB13782
unconjugated
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- Target See all ABCG2 Antibodies
- ABCG2 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2))
- Binding Specificity
- AA 305-335, Center
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ABCG2 antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- This ABCG2 (BCRP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313~342 amino acids from the center region of human ABCG2.
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This ABCG2 (BCRP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-335 AA from the Central region of human ABCG2 (BCRP).
- Clone
- RB13782
- Isotype
- Ig Fraction
- Top Product
- Discover our top product ABCG2 Primary Antibody
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anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2) (AA 305-335) antibody
ABCG2 Reactivity: Human WB, FACS, IF, ELISA, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB = 1:1000, IF = 1:10-50, FACS = 1:10-50, IHC (p) = 1:50-100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 2 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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- Target
- ABCG2 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2))
- Alternative Name
- ABCG2 (BCRP) (ABCG2 Products)
- Background
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ABCG2 is a membrane-associated protein included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.
Synonyms: ATP-binding cassette sub-family G member 2, Placenta-specific ATP-binding cassette transporter, Breast cancer resistance protein, Mitoxantrone resistance-associated protein, CD338 antigen, CDw338, ABCP, BCRP, BCRP1, MXR - Molecular Weight
- 72314 DA
- Gene ID
- 9429
- UniProt
- Q9UNQ0
- Pathways
- Transition Metal Ion Homeostasis
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