SLC16A1 antibody (C-Term)

Catalog No. ABIN389230

Product Details anti-SLC16A1 Antibody

Target: SLC16A1 (Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1))

Binding Specificity: AA 430-460, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC16A1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This MCT1 (SLC16A1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 430-460 amino acids from the C-terminal region of human MCT1 (SLC16A1).

Clone: RB15099

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C.

Expiry Date: 6 months

References for anti-SLC16A1 antibody (ABIN389230)

Ideno, Sasaki, Kobayashi, Futagi, Narumi, Iseki: "Influence of high glucose state on bromopyruvate-induced cytotoxity by human colon cancer cell lines." in: Drug metabolism and pharmacokinetics, Vol. 31, Issue 1, pp. 67-72, (2016) (PubMed).

Target Details for SLC16A1

Target: SLC16A1 (Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1))

Alternative Name: MCT1 (SLC16A1) (SLC16A1 Products)

Background: SLC16A1 is a monocarboxylate transporter (MCT1) that mediates the movement of lactate and pyruvate across cell membranes import and export of these substrates by tissues such as erythrocytes, muscle, intestine, and kidney are ascribed largely to the action of a proton-coupled MCT (Garcia et al., 1994 [PubMed 8124722]).

Molecular Weight: 53944

NCBI Accession: NP_001159968, NP_003042

UniProt: P53985

Pathways: Warburg Effect