SLC16A1 antibody (Internal Region)

Catalog No. ABIN6266268

Product Details anti-SLC16A1 Antibody

Target: SLC16A1 (Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC16A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: SLC16A1 Antibody detects endogenous levels of total SLC16A1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SLC16A1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SLC16A1

Target: SLC16A1 (Solute Carrier Family 16, Member 1 (Monocarboxylic Acid Transporter 1) (SLC16A1))

Alternative Name: SLC16A1 (SLC16A1 Products)

Synonyms: HHF7 antibody, MCT antibody, MCT1 antibody, MCT1a antibody, cb517 antibody, zgc:55682 antibody, slc16a1 antibody, MGC52993 antibody, SLC16A1 antibody, DKFZp469B1212 antibody, AL022710 antibody, Mct1 antibody, RATMCT1 antibody, RNMCT1 antibody, solute carrier family 16 member 1 antibody, solute carrier family 16 (monocarboxylate transporter), member 1b antibody, solute carrier family 16 member 1 S homeolog antibody, solute carrier family 16 (monocarboxylic acid transporters), member 1 antibody, SLC16A1 antibody, slc16a1b antibody, slc16a1.S antibody, Slc16a1 antibody

Background:

Description: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

Gene: SLC16A1

Molecular Weight: 54kDa

Gene ID: 6566

UniProt: P53985

Pathways: Warburg Effect