AMHR2 antibody (N-Term)

Catalog No. ABIN391173

Product Details anti-AMHR2 Antibody

Target: AMHR2 (Anti-Mullerian Hormone Receptor, Type II (AMHR2))

Binding Specificity: AA 13-42, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMHR2 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: Rb

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This AMHR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human AMHR2.

Clone: RB8486

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-AMHR2 antibody (ABIN391173)

Almeida, Conley, Ball: "Expression of anti-Müllerian hormone, CDKN1B, connexin 43, androgen receptor and steroidogenic enzymes in the equine cryptorchid testis." in: Equine veterinary journal, Vol. 45, Issue 5, pp. 538-45, (2013) (PubMed).

Almeida, Conley, Mathewson, Ball: "Expression of anti-Müllerian hormone, cyclin-dependent kinase inhibitor (CDKN1B), androgen receptor, and connexin 43 in equine testes during puberty." in: Theriogenology, Vol. 77, Issue 5, pp. 847-57, (2012) (PubMed).

Almeida, Ball, Conley, Place, Liu, Scholtz, Mathewson, Stanley, Moeller: "Biological and clinical significance of anti-Müllerian hormone determination in blood serum of the mare." in: Theriogenology, Vol. 76, Issue 8, pp. 1393-403, (2011) (PubMed).

Target Details for AMHR2

Target: AMHR2 (Anti-Mullerian Hormone Receptor, Type II (AMHR2))

Alternative Name: AMHR2 (AMHR2 Products)

Target Type: Antibody

Background: The AMH receptor (AMHR or AMHR2) is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth, anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes.

Molecular Weight: 62750

Gene ID: 269

NCBI Accession: NP_001158162, NP_001158163, NP_065434

UniProt: Q16671