AMHR2 antibody (C-Term)

Catalog No. ABIN391175

There is 1 publication for this product available. The Rabbit Polyclonal anti-AMHR2 antibody is suitable to detect AMHR2 in samples from Human. It has been validated for FACS.

Quick Overview for AMHR2 antibody (C-Term) (ABIN391175)

Target: AMHR2 (Anti-Mullerian Hormone Receptor, Type II (AMHR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMHR2 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: RB15726

Product Details anti-AMHR2 Antibody

Binding Specificity: AA 374-402, C-Term

Predicted Reactivity: M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This AMHR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-402 amino acids from the C-terminal region of human AMHR2.

Isotype: Ig Fraction

Application Details

Application Notes: FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-AMHR2 antibody (ABIN391175)

Carrarelli, Rocha, Belmonte, Zupi, Abrão, Arcuri, Piomboni, Petraglia: "Increased expression of antimüllerian hormone and its receptor in endometriosis." in: Fertility and sterility, Vol. 101, Issue 5, pp. 1353-8, (2014) (PubMed).

Target Details for AMHR2

Target: AMHR2 (Anti-Mullerian Hormone Receptor, Type II (AMHR2))

Alternative Name: AMHR2

Target Type: Antibody

Background: The AMH receptor (AMHR or AMHR2) is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth, anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes.

Molecular Weight: 62750

Gene ID: 269

NCBI Accession: NP_001158162, NP_001158163, NP_065434

UniProt: Q16671