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Connexin 43/GJA1 antibody (Internal Region)

GJA1 Reactivity: Human, Rat, Dog, Pig WB Host: Goat Polyclonal unconjugated
Catalog No. ABIN452424
  • Target See all Connexin 43/GJA1 (GJA1) Antibodies
    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
    Binding Specificity
    • 22
    • 16
    • 11
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 125
    • 88
    • 86
    • 31
    • 11
    • 10
    • 8
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Dog, Pig
    Host
    • 127
    • 6
    • 3
    • 1
    Goat
    Clonality
    • 130
    • 6
    Polyclonal
    Conjugate
    • 81
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Connexin 43/GJA1 antibody is un-conjugated
    Application
    • 96
    • 52
    • 49
    • 21
    • 20
    • 16
    • 13
    • 13
    • 10
    • 9
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    This antibody reacts to Connexin 43.
    Cross-Reactivity (Details)
    Species reactivity (expected):Human, Canine, Porcine.
    Species reactivity (tested):Rat.
    Purification
    Affinity chromatography
    Immunogen
    Peptide with sequence C-QPFDFPDDNQNSKK, from the internal region of the protein sequence
    Top Product
    Discover our top product GJA1 Primary Antibody
  • Application Notes
    Peptide ELISA: 1/64000. Western blot: 0.3 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0,5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
    Alternative Name
    GJA1 / Cx43 (GJA1 Products)
    Background
    GJA1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. GJA1 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. GJA1 is targeted by several protein kinases that regulate myocardial cell cell coupling. A related intronless GJA1 pseudogene, GJA1P, has been mapped to chromosome 5.Synonyms: Connexin-43, GJAL, Gap junction 43 kDa heart protein, Gap junction alpha-1 protein
    Gene ID
    2697
    NCBI Accession
    NP_000156
    UniProt
    P17302
    Pathways
    MAPK Signaling, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
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