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PRKAA1 antibody (AA 479-510)

PRKAA1 Reactivity: Human, Mouse ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3032383
$578.58
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  • Target See all PRKAA1 Antibodies
    PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
    Binding Specificity
    • 29
    • 17
    • 16
    • 15
    • 13
    • 10
    • 9
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 479-510
    Reactivity
    • 173
    • 133
    • 91
    • 25
    • 10
    • 9
    • 8
    • 8
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 169
    • 22
    • 1
    Rabbit
    Clonality
    • 156
    • 36
    Polyclonal
    Conjugate
    • 93
    • 12
    • 11
    • 10
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    This PRKAA1 antibody is un-conjugated
    Application
    • 114
    • 61
    • 50
    • 41
    • 40
    • 39
    • 36
    • 21
    • 13
    • 10
    • 9
    • 3
    • 3
    • 1
    ELISA, Western Blotting (WB)
    Purification
    Purified
    Immunogen
    A portion of amino acids 479-510 from the human protein was used as the immunogen for this AMPK antibody.
    Isotype
    Ig Fraction
  • Application Notes
    Titration of the AMPK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the AMPK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
    Alternative Name
    AMPK (PRKAA1) (PRKAA1 Products)
    Synonyms
    AMPK antibody, AMPKa1 antibody, cb116 antibody, im:7154392 antibody, sb:cb130 antibody, wu:fa94c10 antibody, AMPK1 antibody, AMPKalpha1 antibody, AI194361 antibody, AI450832 antibody, AL024255 antibody, C130083N04Rik antibody, ampk antibody, ampka1 antibody, PRKAA1 antibody, protein kinase AMP-activated catalytic subunit alpha 1 antibody, protein kinase, AMP-activated, alpha 1 catalytic subunit antibody, protein kinase, AMP-activated, alpha 1 catalytic subunit L homeolog antibody, PRKAA1 antibody, prkaa1 antibody, Prkaa1 antibody, prkaa1.L antibody
    Background
    AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. It appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. AMPK alpha 1, a member of the Ser/Thr protein kinase family, is a catalytic subunit of AMPK.
    UniProt
    Q13131
    Pathways
    AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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