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PRKAB2 antibody (AA 3-33)

PRKAB2 Reactivity: Human, Mouse ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3032387
$578.58
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  • Target See all PRKAB2 Antibodies
    PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
    Binding Specificity
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3-33
    Reactivity
    • 19
    • 12
    • 11
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 15
    • 3
    • 1
    Rabbit
    Clonality
    • 16
    • 3
    Polyclonal
    Conjugate
    • 19
    This PRKAB2 antibody is un-conjugated
    Application
    • 16
    • 8
    • 8
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Purification
    Antigen affinity purified
    Immunogen
    A portion of amino acids 3-33 from human PRKAB2 was used as the immunogen for this AMPK beta 2 antibody.
    Isotype
    Ig Fraction
  • Application Notes
    Titration of the AMPK beta 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the AMPK beta 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
    Alternative Name
    AMPK beta 2 (PRKAB2) (PRKAB2 Products)
    Synonyms
    prkab2 antibody, MGC64365 antibody, PRKAB2 antibody, DKFZp469M1118 antibody, 5730553K21Rik antibody, AW049591 antibody, BB124140 antibody, protein kinase, AMP-activated, beta 2 non-catalytic subunit L homeolog antibody, protein kinase AMP-activated non-catalytic subunit beta 2 antibody, protein kinase, AMP-activated, beta 2 non-catalytic subunit antibody, prkab2.L antibody, PRKAB2 antibody, prkab2 antibody, Prkab2 antibody
    Background
    The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.
    UniProt
    O43741
    Pathways
    AMPK Signaling
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