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NFATC1 antibody (AA 898-927)

NFATC1 Reactivity: Human IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3032038
$578.58
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  • Target See all NFATC1 Antibodies
    NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
    Binding Specificity
    • 16
    • 11
    • 11
    • 10
    • 9
    • 8
    • 7
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 898-927
    Reactivity
    • 114
    • 51
    • 28
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    Human
    Host
    • 103
    • 10
    • 1
    Rabbit
    Clonality
    • 97
    • 17
    Polyclonal
    Conjugate
    • 49
    • 9
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NFATC1 antibody is un-conjugated
    Application
    • 65
    • 38
    • 30
    • 17
    • 13
    • 13
    • 9
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Purification
    Antigen affinity purified
    Immunogen
    A portion of amino acids 898-927 from the human protein was used as the immunogen for this NFATC1 antibody.
    Isotype
    Ig Fraction
  • Application Notes
    Titration of the NFATC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the NFATC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
    Alternative Name
    NFATC1 (NFATC1 Products)
    Synonyms
    nf-atc antibody, nfat2 antibody, nfatc antibody, si:ch211-198c22.2 antibody, NFATC1 antibody, 2210017P03Rik antibody, AI449492 antibody, AV076380 antibody, NF-ATc antibody, NFAT2 antibody, NFATc antibody, Nfatcb antibody, NF-ATC antibody, NF-ATc1 antibody, NFAT antibody, NFATmac antibody, nuclear factor of activated T-cells 1 antibody, nuclear factor of activated T-cells 1 L homeolog antibody, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 antibody, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 antibody, NFATC1 antibody, nfatc1.L antibody, nfatc1 antibody, Nfatc1 antibody
    Background
    The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
    UniProt
    O95644
    Pathways
    RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway
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