MAPK14 antibody (AA 295-324)
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- Target See all MAPK14 Antibodies
- MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))
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Binding Specificity
- AA 295-324
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MAPK14 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
- Cross-Reactivity (Details)
- Expected species reactivity: Mouse
- Purification
- Antigen affinity purified
- Immunogen
- A portion of amino acids 295-324 from the human protein was used as the immunogen for this p38 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product MAPK14 Primary Antibody
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- Application Notes
- Titration of the p38 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the p38 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))
- Alternative Name
- p38 (MAPK14) (MAPK14 Products)
- Background
- P38 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.
- UniProt
- Q16539
- Pathways
- MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins
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