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PTBP1 antibody (AA 26-55)

PTBP1 Reactivity: Human ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3032275
$578.58
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  • Target See all PTBP1 Antibodies
    PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))
    Binding Specificity
    • 17
    • 14
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 26-55
    Reactivity
    • 72
    • 27
    • 25
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 59
    • 7
    • 6
    Rabbit
    Clonality
    • 56
    • 16
    Polyclonal
    Conjugate
    • 29
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This PTBP1 antibody is un-conjugated
    Application
    • 46
    • 31
    • 18
    • 9
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Cross-Reactivity (Details)
    Expected species reactivity: Bovine
    Purification
    Antigen affinity purified
    Immunogen
    A portion of amino acids 26-55 from the human protein was used as the immunogen for this PTBP1 antibody.
    Isotype
    Ig Fraction
  • Application Notes
    Titration of the PTBP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the PTBP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))
    Alternative Name
    PTBP1 (PTBP1 Products)
    Synonyms
    HNRNP-I antibody, HNRNPI antibody, HNRPI antibody, PTB antibody, PTB-1 antibody, PTB-T antibody, PTB2 antibody, PTB3 antibody, PTB4 antibody, pPTB antibody, Ptb antibody, hnrpi antibody, hnrnp-I antibody, vgrbp60 antibody, AA407203 antibody, AL033359 antibody, Pybp antibody, Pybp1 antibody, Pybp2 antibody, ptbp1 antibody, wu:fb99f12 antibody, zgc:110689 antibody, ptb antibody, ATPTB1 antibody, POLYPYRIMIDINE TRACT-BINDING antibody, POLYPYRIMIDINE TRACT-BINDING PROTEIN 1 antibody, T4P13.16 antibody, T4P13_16 antibody, polypyrimidine tract-binding protein 1 antibody, PTBP1 antibody, polypyrimidine tract binding protein 1 antibody, polypyrimidine tract binding protein 1 S homeolog antibody, polypyrimidine tract-binding protein antibody, polypyrimidine tract binding protein 1a antibody, polypyrimidine tract binding protein 1 L homeolog antibody, polypyrimidine tract-binding protein 1 antibody, PTBP1 antibody, ptbp1.S antibody, NAEGRDRAFT_80143 antibody, LOC100285404 antibody, Ptbp1 antibody, ptbp1a antibody, ptbp1.L antibody, PTB1 antibody, LOC100061673 antibody
    Background
    This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described.
    UniProt
    P26599
    Pathways
    Regulation of Muscle Cell Differentiation
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