Sonic Hedgehog antibody (N-Term)
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- Target See all Sonic Hedgehog (SHH) Antibodies
- Sonic Hedgehog (SHH)
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Binding Specificity
- N-Term
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Sonic Hedgehog antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Antigen affinity purified
- Immunogen
- This mouse Shh antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 58-91 amino acids from the N-terminal region of mouse Sonic hedgehog.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product SHH Primary Antibody
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anti-Sonic Hedgehog (SHH) (AA 21-120) antibody
SHH Reactivity: Human, Mouse, Rat, Pig WB, ELISA, IF (cc), IHC (p), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Sonic Hedgehog (SHH) (AA 26-161) antibodySHH Reactivity: Human WB, IHC, ELISA, FACS Host: Mouse Monoclonal 5H4 unconjugated
anti-Sonic Hedgehog (SHH) (C-Term) antibodyVerified SHH Reactivity: Human, Mouse WB, ELISA, IF, FACS Host: Goat Polyclonal unconjugated
anti-Sonic Hedgehog (SHH) (N-Term) antibodySHH Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Cow, Guinea Pig, Horse, Goat, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Sonic Hedgehog (SHH) (AA 26-161) antibodySHH Reactivity: Human, Mouse, Monkey WB, IHC, ELISA, FACS Host: Mouse Monoclonal unconjugated
anti-Sonic Hedgehog (SHH) (AA 36-193) antibodySHH Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Sonic Hedgehog (SHH) (AA 36-193) antibodySHH Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal D6 unconjugated
anti-Sonic Hedgehog (SHH) (AA 58-91), (N-Term) antibodySHH Reactivity: Human, Mouse, Rat WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB52387 unconjugated
anti-Sonic Hedgehog (SHH) (AA 24-197) antibodySHH Reactivity: Human, Rat, Dog, Monkey WB, IF Host: Mouse Monoclonal 10H6 unconjugated
anti-Sonic Hedgehog (SHH) (AA 237-399) antibodySHH Reactivity: Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
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Titration of the Shh antibody may be required due to differences in protocols and secondary/substrate sensitivity.
1. The 45 kDa precursor protein autocleaves into 27 kDa amino and 19 kDa carboxy fragments.\. Western blot: 1:1000-2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the Shh antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- Sonic Hedgehog (SHH)
- Alternative Name
- Shh (SHH Products)
- Background
- Sonic hedgehog intercellular signaling is essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO. [UniProt]
- UniProt
- Q62226
- Pathways
- Hedgehog Signaling, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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