G6PC3 antibody (Glucose 6-Phosphatase, Catalytic 3) (Alexa Fluor 680)

Details for Product anti-G6PC3 Antibody No. ABIN5003033
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
20
19
17
4
4
4
4
3
2
1
1
1
1
Host
Rabbit
20
Clonality
Polyclonal
Conjugate
This G6PC3 antibody is conjugated to Alexa Fluor 680
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
12
8
4
2
1
Options
Immunogen KLH conjugated synthetic peptide derived from human G6PC3
Isotype IgG
Purification Purified by Protein A.
Antigen
Alternative Name G6PC3 (G6PC3 Antibody Abstract)
Background

Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate (G6P) in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-Alpha, a second form, designated G6Pase-Beta, contributes to blood glucose homeostasis in a wider range of tissues. G6Pase-Beta, also known as SCN4, UGRP or G6PC3 (glucose 6 phosphatase, catalytic, 3), is a 346 amino acid endoplasmic reticulum multi-pass membrane protein that is involved in carbohydrate biosynthesis and the gluconeogenesis pathway. Inhibited by vanadate, G6Pase-Beta hydrolyzes GP6 to glucose in the endoplasmic reticulum. Due to its necessary involvement in normal glucose metabolism, G6Pase-Beta may play an integral role in diabetes and glycogen storage diseases (GSDs).

Synonyms: G-6-Pase 3, G6Pase 3, G6Pase-beta, Glucose 6 phosphatase, catalytic, 3, Glucose-6-phosphatase 3, Glucose-6-phosphatase beta, SCN4, Ubiquitous glucose-6-phosphatase catalytic subunit-related protein, UGRP,

Gene ID 92579
Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months