G6PC3 antibody (N-Term)

Catalog No. ABIN2789897

The Rabbit Polyclonal anti-G6PC3 antibody (ABIN2789897) specifically detects G6PC3 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse, Sheep and Zebrafish (Danio rerio) samples.

Quick Overview for G6PC3 antibody (N-Term) (ABIN2789897)

Target: G6PC3 (Glucose 6-Phosphatase, Catalytic 3 (G6PC3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This G6PC3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-G6PC3 Antibody

Binding Specificity: N-Term

Purpose: G6PC3 Antibody - N-terminal region

Sequence: ESGYYSQAPA QVHQFPSSCE TGPGSPSGHC MITGAALWPI MTALSSQVAT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 85%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against G6PC3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human G6PC3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64608-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for G6PC3

Target: G6PC3 (Glucose 6-Phosphatase, Catalytic 3 (G6PC3))

Alternative Name: G6PC3

Background:

Background Information: This gene encodes the catalytic subunit of glucose-6-phosphatase (G6Pase). G6Pase is located in the endoplasmic reticulum (ER) and catalyzes the hydrolysis of glucose-6-phosphate to glucose and phosphate in the last step of the gluconeogenic and glycogenolytic pathways. Mutations in this gene result in autosomal recessive severe congenital neutropenia. Multiple transcript variants have been found for this gene, only one of which is expected to express a protein.

Gene Name: Glucose 6 phosphatase, catalytic, 3

Alternative Symbols: SCN4, UGRP

Protein Name: Glucose-6-phosphatase 3

Molecular Weight: 39kDa

Gene ID: 92579

NCBI Accession: NP_612396

UniProt: Q9BUM1