Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

SLC9A1 antibody (Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1) (C-Term) Primary Antibody

SLC9A1 Reactivity: Human, Mouse, Rat EIA, IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500339
$598.40
Plus shipping costs $45.00
0.1 mg
local_shipping Shipping to: United States
Available
  • Target
    SLC9A1
    Binding Specificity
    • 15
    • 12
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term, N-Term
    Reactivity
    • 36
    • 33
    • 25
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 41
    • 5
    • 3
    Rabbit
    Clonality
    • 44
    • 5
    Polyclonal
    Conjugate
    • 28
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC9A1 antibody is un-conjugated
    Application
    • 34
    • 25
    • 13
    • 13
    • 10
    • 9
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Specificity
    This antibody detects SLC9A1 / NHE1 at N-term.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogen
    Nhe-1 antibody was raised against a 20 amino acid peptide near the carboxy terminus of the human Nhe-1.
    Isotype
    IgG
  • Application Notes
    ELISA. Western blot. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    SLC9A1
    Alternative Name
    SLC9A1 / NHE1 (SLC9A1 Antibody Abstract)
    Synonyms
    AT-NHX1, ATNHX, ATNHX1, NA(+)/H(+) ANTIPORTER, Na+/H+ exchanger 1, T21B4.60, T21B4_60, AW554487, Apnh, Nhe1, swe, NHE-1, NHE1, APNH, Na+/H+ exchanger 1, solute carrier family 9 (sodium/hydrogen exchanger), member 1, solute carrier family 9 member A1, NHX1, Slc9a1, SLC9A1
    Background
    The Na+/H+ antiporter (Nhe-1) is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells and is specifically inhibited by the diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, and tumor promoters. Nhe-1 acts as an anchor for actin filaments to control the integrity of the cortical cytoskeleton. This occurs through a previously unrecognized structural link between Nhe-1 and the actin-binding proteins ezrin, radixin, and moesin, collectively referred to as ERM proteins. A structural role for Nhe-1 has been proposed in regulating the cortical cytoskeleton that is independent of its function as an ion exchanger. It is also thought that Nhe-1 play a role in hypertension. At least two isoforms of Nhe-1 are known to exist.Synonyms: APNH, APNH1, Na(+)/H(+) antiporter, Na(+)/H(+) exchanger 1, Sodium/hydrogen exchanger 1, Solute carrier family 9 member 1, amiloride-sensitive
    Gene ID
    6548
    UniProt
    P19634
    Pathways
    Glycosaminoglycan Metabolic Process, Proton Transport
You are here:
help Support