RAD52 antibody (Middle Region)

Catalog No. ABIN5515096

The Rabbit Polyclonal anti-RAD52 antibody has been validated for WB. It is suitable to detect RAD52 in samples from Human.

Quick Overview for RAD52 antibody (Middle Region) (ABIN5515096)

Target: RAD52 (RAD52 Homolog (S. Cerevisiae) (RAD52))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD52 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAD52 Antibody

Binding Specificity: Middle Region

Sequence: LNNGKFYVGV CAFVRVQLKD GSYHEDVGYG VSEGLKSKAL SLEKARKEAV

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RAD52

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RAD52

Target: RAD52 (RAD52 Homolog (S. Cerevisiae) (RAD52))

Alternative Name: RAD52

Background: The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Protein Size: 301

Gene ID: 5893

NCBI Accession: NM_001297422, NP_001284348

UniProt: F5GX32

Pathways: DNA Damage Repair