EHD2 antibody (N-Term)

Catalog No. ABIN5516007

Product Details anti-EHD2 Antibody

Target: EHD2 (EH-Domain Containing 2 (EHD2))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EHD2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SFIQYLLEQE VPGSRVGPEP TTDCFVAVMH GDTEGTVPGN ALVVDPDKPF

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EHD2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EHD2

Target: EHD2 (EH-Domain Containing 2 (EHD2))

Alternative Name: EHD2 (EHD2 Products)

Background: This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway.

Alias Symbols: PAST2

Protein Size: 543

Gene ID: 30846

NCBI Accession: NM_014601, NP_055416

UniProt: Q9NZN4

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development