ID1 antibody (Middle Region)

Catalog No. ABIN5516062

Product Details anti-ID1 Antibody

Target: ID1 (Inhibitor of DNA Binding 1, Dominant Negative Helix-Loop-Helix Protein (ID1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ID1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: YDMNGCYSRL KELVPTLPQN RKVSKVEILQ HVIDYIRDLQ LELNSESEVG

Predicted Reactivity: Cow: 100%, Dog: 77%, Guinea Pig: 100%, Horse: 80%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 87%

Characteristics: This is a rabbit polyclonal antibody against ID1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human ID1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ID1

Target: ID1 (Inhibitor of DNA Binding 1, Dominant Negative Helix-Loop-Helix Protein (ID1))

Alternative Name: ID1 (ID1 Products)

Background: The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: ID1, BHLHB24, ID,

Protein Interaction Partner: UBC, SUV39H1, PPP2CA, CAV1, TCF4, COPB1, FZR1, RASSF1, CDC20, HHV8GK18_gp81, TCF3, PSMD4, SMURF2, IKBKG, GATA4, NKX2-5, MYOD1, TCF12, ELK4, ELK1, CASK, MYF6, MYF5, MYOG, IFI16, HES1, RUNX1T1, ELSPBP1,

Protein Size: 155

Gene ID: 3397

UniProt: P41134