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C1QL3 antibody (Middle Region)
C1QL3
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-C1QL3 Antibody
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Target
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C1QL3
(Complement Component 1, Q Subcomponent-Like 3 (C1QL3))
Binding Specificity
All epitopes for C1QL3 antibodies
Middle Region
Reactivity
All reactivities for C1QL3 antibodies
Human
Host
All hosts for C1QL3 antibodies
Rabbit
Clonality
All clonalities for C1QL3 antibodies
Polyclonal
Conjugate
All conjugates for C1QL3 antibodies
This C1QL3 antibody is un-conjugated
Application
All applications for C1QL3 antibodies
Western Blotting (WB)
Sequence
VPKIAFYAGL KRQHEGYEVL KFDDVVTNLG NHYDPTTGKF TCSIPGIYFF
Characteristics
This is a rabbit polyclonal antibody against C1QL3. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human C1QL3
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for C1QL3
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Target
C1QL3
(Complement Component 1, Q Subcomponent-Like 3 (C1QL3))
Alternative Name
C1QL3 (C1QL3 Products )
Synonyms
1110065A22Rik antibody, AI661623 antibody, C1ql antibody, C1qtnf13 antibody, CTRP13 antibody, K100 antibody, C1QTNF13 antibody, zgc:77412 antibody, C1q-like 3 antibody, complement C1q like 3 antibody, complement component 1, q subcomponent-like 3b antibody, C1ql3 antibody, C1QL3 antibody, c1ql3b antibody
Background
C1QL3 may regulate the number of excitatory synapses that are formed on hippocampus neurons. It has no effect on inhibitory synapses . It plays a role in glucose homeostasis. Via AMPK signaling pathway, C1QL3 stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, C1QL3 reduces the expression of gluconeogenic enzymes G6PC and PCK1 and hence decreases de novo glucose production. Alias Symbols: C1QL3, CTRP13, Protein Interaction Partner: SERPINH1, Protein Size: 255
Gene ID
389941
NCBI Accession
NP_001010908
UniProt
Q5VWW1
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