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MLF1 antibody (N-Term)

MLF1 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5531591
  • Target See all MLF1 Antibodies
    MLF1 (Myeloid Leukemia Factor 1 (MLF1))
    Binding Specificity
    • 13
    • 8
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 35-62, N-Term
    Reactivity
    • 65
    • 46
    • 20
    • 1
    • 1
    Human, Mouse
    Host
    • 62
    • 5
    Rabbit
    Clonality
    • 64
    • 3
    Polyclonal
    Conjugate
    • 36
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MLF1 antibody is un-conjugated
    Application
    • 53
    • 21
    • 20
    • 16
    • 13
    • 9
    • 7
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    Immunogen
    This MLF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-62 amino acids from the N-terminal region of human MLF1.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MLF1 Primary Antibody
  • Application Notes
    For WB starting dilution is: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    MLF1 (Myeloid Leukemia Factor 1 (MLF1))
    Alternative Name
    MLF1 (MLF1 Products)
    Background
    MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
    Molecular Weight
    31 kDa
    Gene ID
    4291
    UniProt
    P58340
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